Sealed Human Lens Capsule Irrigation

Abstract

Abstract: : Purpose: To assess a delivery system which allows infusion of fluid into the capsular bag of human eyes without contacting the surrounding ocular tissues Method: This study was performed in 24 human eyes during cataract surgery. The delivery system was used to infuse trypan blue into the human lens capsule of 12 eyes after removal of the cataract. The dye was then removed, without contacting the surrounding intraocular tissues. Samples of anterior chamber fluid were taken after infusion and after removal to quantify leakage from the human capsular bag. Dye concentration was assessed using a spectrophotometer. Results were compared with anterior chamber samples taken from the anterior chamber of 12 eyes without using the delivery system. Results: A statistically significant reduction in anterior chamber concentration of trypan blue was achieved when the delivery system was utilized Conclusion: Controlled delivery of fluid into the capsular bag can occur using this method. Surrounding ocular tissues are not contaminated by capsule irrigation fluid.

Keywords: 522 posterior capsular opacification (PCO) • 582 small incision cataract surgery • 341 cell death/apoptosis