December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Chronic Central Serous Chorioretinopathy Presenting with Peripheral Lipid Exudation
Author Affiliations & Notes
  • IM Donsoff
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • AP Ciardella
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • DL L Costa
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • SJ Huang
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • N Borodoker
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • MF Marmor
    Department of Ophthalmology Stanford University Medical Center Stanford CA
  • LA Yannuzzi
    LuEsther T Mertz Retinal Research Center Manhattan Eye Ear and Throat Hospital New York NY
  • Footnotes
    Commercial Relationships   I.M. Donsoff, None; A.P. Ciardella, None; D.L.L. Costa, None; S.J. Huang, None; N. Borodoker, None; M.F. Marmor, None; L.A. Yannuzzi, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 491. doi:
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    • Get Citation

      IM Donsoff, AP Ciardella, DL L Costa, SJ Huang, N Borodoker, MF Marmor, LA Yannuzzi; Chronic Central Serous Chorioretinopathy Presenting with Peripheral Lipid Exudation . Invest. Ophthalmol. Vis. Sci. 2002;43(13):491.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: Dependent exudative detachments may be due to a myriad of chorioretinal disorders including neovascular maculopathies, inflammatory and infiltrative uveal scleral diseases, vasoproliferative abnormalities, and chronic central serous chorioretinopathy. Chronic detachments may also result in a secondary retinal microangiopathy with telangiectasias, non-perfusion, and neovascularization. We describe the appearance of peripheral lipid exudation and modulation of the peripheral microangiopathy following the resolution of a dependent detachment in patients with chronic central serous chorioretinopathy. Method: Retrospective chart review. Results: Four patients with chronic central serous chorioretinopathy and a peripheral dependent detachment with secondary microangiopathy were identified. One patient had history of systemic lupus; one patient had undergone organ transplantation, and one patient was pregnant at the time of diagnosis. Two patients received systemic corticosteroid treatment prior to diagnosis. Following the treatment to posterior retinal pigment epithelium leak and resolution of the detachment, all patients developed lipid precipitation in the peripheral retina. There was also remodeling of the retinal circulation including regression of telangiectasias and neovascularization after the detachment has resolved. Conclusion: Peripheral lipid deposition and remodeling of retinal circulation may develop following the resolution of dependent detachment secondary to chronic central serous chorioretinopathy. It is not necessary to treat the peripheral detachment to restore normal retinal circulation. Eventual regression of the precipitated lipid and associated intraretinal telangiectasias, retinal ischemia, and neovascularization was observed after the resolution of the dependent detachment.

Keywords: 554 retina • 566 retinal neovascularization • 567 retinal pigment epithelium 
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