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IP Glavas, J Young; Fractal Density of Normal Versus Abnormal Vascular Patterns Seen in Intravenous Fluorescein Angiogram (IFVA) Photographs of Normal and Abnormal Eyes with Branch Retinal Vein Obstruction . Invest. Ophthalmol. Vis. Sci. 2002;43(13):520.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To analyze and compare the fractal density (FD) of normal versus abnormal vascular patterns seen in intravenous fluorescein angiogram (IFVA) photographs or eyes with branch retinal vein occlusion (BRVO). Methods: Ten eyes of five patients were selected. Pairs of one normal and one abnormal, including the BRVO lesion, IVFA samples were digitized. The resulting images were analyzed using fractal analysis software. Fractal dimension analysis was performed for each one of the samples as a whole. Also, segments of the digitized samples that included the affected retinal area were analyzed. Results: Comparison of sample pairs of normal (FD=1.89) versus abnormal IVFA parts including the BRVO lesion (FD=1.79) showed a statistically significant difference (p=0.042) in the fractal dimension values. Conclusion: The study suggests that there is a real difference between the fractal density of the normal and BRVO abnormal vascular patterns. The difference of fractal dimension between normal and abnormal vascular patterns in the same patient may suggest a new method of recognizing retinal areas of pathologic vasculature.
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