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MM Altaweel; Intravitreal Steroid Injection for Management of Chronic Macular Edema Caused by CRVO . Invest. Ophthalmol. Vis. Sci. 2002;43(13):529.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To demonstrate the efficacy of intravitreal triamcinolone injection for treatment of refractory macular edema caused by central retinal vein occlusion. Methods: 48 year old male with nonischemic CRVO with no change in vision after 3 months of observation, or in the 2 months following a subtenons steroid injection. Intravitreal injection of 0.4 mg (0.1 ml) of Triamcinolone was administered. Baseline hematologic evaluation was performed. Masked ETDRS vision, biomicroscopy, fundus photography, fluorescein angiography, and OCT were obtained at all timepoints. Results: VA improved from 34 letters (20/200) before injection to 71 letters (20/40) within 2 weeks and is maintained at 6 month follow-up. Macular thickness on OCT decreased from 600 um to 150 um. Biomicroscopic and angiographic cystoid edema resolved completely. Intraocular pressure remained normal. Conclusion: A single intravitreal injection of steroid successfully resolved macular edema caused by CRVO, with marked visual improvement, and with no adverse side effect. This therapy involves less risk than radial neurotomy or laser chorioretinal anastamosis formation and will be evaluated in a randomized controlled clinical trial.
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