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C Chiquet, M Quaranta, M Mauget, D Stanescu, G Coscas; Exudative Idiopathic Polypoidal Choroidal Vasculopathy and Photodynamic Therapy with Visudyne . Invest. Ophthalmol. Vis. Sci. 2002;43(13):591.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To report functional results of photodynamic therapy (PDT) with Visudyne in four patients of acute exudative Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) Methods: In four consecutive patients with recent visual impairment (ETDRS best-corrected visual acuity and Pelli-Robson contrast sensitivity), acute IPCV was diagnosed by fluorescein and ICG angiographies. The retrofoveal location of the exudative polypoidal dilations visualized on either fluorescein or ICG angiography suggested the realisation of PDT treatment with Visudyne. The PDT procedure was the same as for the choroidal neovascularization of age-related macular degeneration. Functional and angiographic outcomes were assessed 6, 12, 24 and 48 weeks after treatment Results: Patients were 3 women and 1 man, mean age was 60 years (range: 58/65). Visual function improved in all cases 6 to 12 weeks after treatment (mean VA before PDT: 10/25, mean VA after PDT 10/12.5. Contrast sensitivity was 0.90 before vs 1.35 after PDT) and then stabilized. Angiographically, PDT with Visudyne allowed to achieve non perfusion and occlusion of the exudative polypoidal dilations immediately after treatment and during the whole follow-up period. No acute recurrence was recorded Conclusion: PDT with Visudyne seems to be a safe and efficient treatment for acute IPCV with retrofoveal polypoidal dilations
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