Abstract
Abstract: :
Purpose: To investigate the influence of post-LASIK corneal healing on RNFLT as measured with GDx nerve fiber analyzer. Methods: Polarimetric RNFLT measurements with the GDx instrument were performed before LASIK, and 1 and 3 days and 3 months after surgery on one randomly selected eye of 20 consecutive healthy subjects with no ocular disease undergoing LASIK for ametropia correction. ANOVA was used for analysis. Results: Sup. avg. RNFLT decreased at all time points compared to baseline (p<0.003) but increased between postoperative day 1 and the final visit (p=0.025). Inf. avg. RNFLT was smaller in the early post-LASIK days than at month 3 (p<0.05) and tended to be smaller than at baseline. No difference was seen, however, between the final and baseline inf. avg. RNFLT values (p=0.69). Ellipse avg. RNFLT was smaller in the early postoperative days than at baseline, but increased again for the last visit (p<0.02), and showed no difference between the baseline and the final visits (p=0.46). Conclusion: RNFLT of the non-glaucomatous, healthy eyes as measured with the GDx nerve fiber analyzer show changes after LASIK, which, however, diminish with the time after surgery, and tend to return to the preoperative values during the first 3 months after uncomplicated LASIK.
Keywords: 484 nerve fiber layer • 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 430 imaging/image analysis: clinical