Abstract
Abstract: :
Purpose:Macular edema is frequently responsible for loss of central vision in patients affected with retinitis pigmentosa (RP). This macular edema can be treated by Acetazolamide. Our purpose was to evaluate optical coherence tomography (OCT) examination in the follow up of macular edema in RP. Furthermore, we tried to evaluate the minimal efficient dose of Acetazolamide, using other means than fundus examination or fluorescein angiography. Methods:We report the cases of five patients affected with typical retinitis pigmentosa and fundus appearance of macular edema.These patients had an oral treatment by Acetazolamide (500mg/d). The OCT examinations were performed before and during treatment Results:OCT examination allowed to evidence, to quantify and monitor the evolution of macular edema during treatment. Conclusion:OCT appears to be a useful tool in the follow up of patients affected with macular edema and RP. This non invasive examination contributes to improve our strategy in treating patients.
Keywords: 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 562 retinal degenerations: hereditary • 460 macula/fovea