December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Macular Holes and Pseudoholes in Retinitis Pigmentosa: Evaluation by RTA
Author Affiliations & Notes
  • E Daniele
    Ophthalmology Univ of Rome Rome Italy
  • M Angelini
    Ophthalmology "la Sapienza" Rome Italy
  • E Vingolo
    Ophthalmology University of Rome Rome Italy
  • Footnotes
    Commercial Relationships   E. Daniele, None; M. Angelini, None; E. Vingolo, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 1185. doi:
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    • Get Citation

      E Daniele, M Angelini, E Vingolo; Macular Holes and Pseudoholes in Retinitis Pigmentosa: Evaluation by RTA . Invest. Ophthalmol. Vis. Sci. 2002;43(13):1185.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: RP represents a group of clinically heterogenous retinal degenerations in which all models of inheritance have been described.Macular changes have been observed in association with RP, although the incidence and possible origins of various lesions have been fully described. Methods: We have analized 50 Rp patient(100 Eyes) with holes or pseudoholes identified after a full ophthalmological examination.All of them were submitted to RTa examination. Rp patient with opacity were not included. an informed consent was obtained. Results:Scanning RTa showed either an intact inner retinal surface or a break in the inner retinal surface at the fovea. A break in the inner retinal surface with no retinal tissue underlying the break was considered to be a full-thickness macular hole by RTA, while a break in the inner retina surface with the possibility of tissue underlying the break was considered as partial thickness macular hole. An epiretinal membrane, saw by RTA as bright speckled reflections adherent or separate from the inner retinal surface, was present in 49 eyes, thickned posterior vitreous surface in 30 eyes, and intraretinal cystic changes in 21 eyes. Conclusion: The pathogenesis of the macular lesions in not always certain; although intraretinal cystuc changes, epiretinal membrane, thickned posterior vitreo surface are present in Rp patients of our study. In this way RTA is very useful to obtain information about diagnosis of macular holes or pseudoholes in Rp patient. In this way we cold prevent holes or pseudoholes formation, also trying to obtain a precise chronology of the events that finished with macular lesions mention above.

Keywords: 357 clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • 310 aging: visual performance • 562 retinal degenerations: hereditary 

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