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N Chng, A Koh; Observational Prospective Study of Polypoidal Choroidal Vasculopathy That Presents Clinically Similar to Central Serous Retinopathy . Invest. Ophthalmol. Vis. Sci. 2002;43(13):1218.
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Purpose: To collect clinical evidence to establish if Polypoidal Choroidal Vasculopathy may present with a clinical picture similar to Central Serous Retinopathy. Introduction: 5 patients, 4 males and 1 female, ages ranging from 45 to 61 years, each presented with central serous retinopathy associated with idiopathic polypoidal choriodal vasculopathy. 3 patients had unilateral features while 2 patients had bilateral features. Presenting symptoms were metamorphopsia, visual deteroriation, and scotoma, and best corrected visual acuities ranged from 6/7.5 to 6/24. None of the patients were on steriods. 3 patients were conservatively managed, and 2 patients received laser treatment. 1 patient who had received laser treatment had a recurrence which required futher laser treatment. Methods: This was a prospective clinical observational study employing bio-ophthalmoscopy, fundus fluroescein angiography, and indo-cyanine green angiography (ICGA). Results:The clinical findings included retinal pigment epithelial disturbances in all patients, and serous elevation in 3 patients. Haemorrhage was not found in any of the patients. Fundus fluorescein angiography findings included multi-focal leaks in 2 patients, retinal pigment epithelial ooze in 1 patient, focal hyperfluoresence corresponding to a fibrin-plaque in 1 patient, and retinal pigment epithelial window defects in all patients. 4 patients demonstrated polypoidal lesions on indo-cyanine angiography, while the remaining patient was presumed to have polypoidal vascular choroidopathy on demonstration of late diffuse choroidal vascular permeability on ICGA. Conclusion: Polypoidal vascular choriodopathy may present with a clinical picture similar to central serous retinopathy.
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