Risk Factors for Hypotony Maculopathy

Abstract

Abstract: : Purpose: To determine the risk factors for hypotony maculopathy. Methods: Chart review of patients with hypotony from one medical center. Hypotony was defined as intraocular pressure less than 6 mm Hg. Cases of hypotony maculopathy had retinal and/or choroidal folds within the arcades. Risk factors were evaluated using multiple logistic regression analysis. Results: 81 case eyes with hypotony maculopathy and 147 control eyes with hypotony alone were identified. Mean age of patients with hypotony maculopathy was 50.5 +/- 18.7 compared to 70.6 +/- 12.7 for the control patients (P<0.001). More patients with hypotony maculopathy were male, 54.3% (44/81), than controls 33.6% (49/147) (P=0.004). The refractive error was -3.02D +/- 3.67D for the phakic eyes with hypotony maculopathy (n=31) whereas the phakic control eyes' (n=30) refractive error was -0.61D +/- 2.00 (P=0.003). 43.2% (35/81) of the hypotony maculopathy eyes underwent primary filtering surgery whereas 25.9% (38/147) of the control eyes underwent primary filtering surgery (P<0.01). Choroidal effusion was found in 21% (17/81) of the case eyes and 52.4% (77/147) of the control eyes (P<0.001). The use of antifibrotics was similar for both groups. Conclusion: Young age, male gender, and myopia are significant risk factors for hypotony maculopathy. Choroidal effusion may be associated with hypotony maculopathy. Table 1. Univariate Risk Factor Analysis  

Keywords: 355 clinical (human) or epidemiologic studies: risk factor assessment • 444 intraocular pressure