December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Retinal Nerve Fiber Layer Thickness and Peripapillary Atrophy in Glaucoma With Small Discs
Author Affiliations & Notes
  • R-M Jun
    Department of Ophthalmology Ewha Womens University Mokdong Hospital Seoul Republic of Korea
  • J Moon
    Ophthalmology St Mary's Hosp Catholic Univ Med Sc Seoul Republic of Korea
  • K-R Choi
    Ophthalmology Ewha Women's University Mokdong Hospital Seoul Republic of Korea
  • Footnotes
    Commercial Relationships   R. Jun, None; J. Moon, None; K. Choi, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 991. doi:
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      R-M Jun, J Moon, K-R Choi; Retinal Nerve Fiber Layer Thickness and Peripapillary Atrophy in Glaucoma With Small Discs . Invest. Ophthalmol. Vis. Sci. 2002;43(13):991.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To evaluate the usefulness of the retinal nerve fiber layer thickness and peripapillary atrophy in discrimination between normal and glaucoma patients with small optic discs which can be potentially misleading by cup-to-disc ratio. Methods: Eyes with average disc diameter 1.617mm or less which is 33 percentile by topographic scanning system(TopSSTM, version 2.2, LDT, Inc., U.S.A) in our normal population study were enrolled. 82 eyes of 82 normal subjects, 30 eyes of 30 patients with primary open-angle glaucoma(POAG), 16 eyes of 16 patients with normal tension glaucoma(NTG) were studied. Program 30-2 of the Humphrey Field and scanning laser polarimetry(Nerve Fiber Analyzer II : NFAII, version 2.1., LDT, Inc., U.S.A.) were performed and color optic disc photographs had been taken. The differences in NFA parameters and peripapillary atrophy(zoneα and zoneß) between normal subjects and glaucoma patients were examined. Results: Considering all the NFA parameters, superonasal ratio of POAG and NTG group was significantly lower than normal group(p=0.002, p=0.043, respectively) and inferonasal ratio of POAG group was significantly lower than normal group(p=0.020). Zone beta atrophy was detected more frequently in POAG and NTG group than normal group(p=0.015, 0.007, respectively). No significant correlation was found between superonasal, inferonsal ratio and visual field indices and the presence of zone beta was not associated with progression of visual field. Conclusions: In small optic discs which had been presented diagnostic difficulties with optic disc status, retinal nerve fiber layer thickness(superonasal or inferonasal ratio) and/or peripapillary atrophy(zone beta) analysis can be helpful in identifying glaucoma.

Keywords: 498 optic disc • 430 imaging/image analysis: clinical 

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