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A Kychenthal, X Katz, P Dorta, R Stevenson; Diode Laser Photocoagulation and Vitrectomy for the Management of Retinopathy of Prematurity in Chile . Invest. Ophthalmol. Vis. Sci. 2002;43(13):1248.
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Purpose:To study the clinical characteristics and treatment outcome after laser and surgical treatment in a series of infants with Retinopathy of Prematurity (ROP). Methods:Forty consecutive eyes in 20 infants with zone I ROP and 93 eyes in 49 infants with zone II ROP were treated with indirect diode laser. In the Zone I group two anatomical subgroups (anterior and posterior) were defined. Additionally, 28 eyes with retinal detachment secondary to ROP were surgically treated. Structural outcome was evaluated at three months. Results:In the laser group 20 out of 40 eyes (50%) with zone I ROP had unfavorable outcome compared with 6 out of 93 eyes (6.5%) with zone II ROP (p < 0.001). Treatment age was significantly less (p=0.001) for zone I group than for zone II group (35.7 vs 37.2 weeks). Fourteen out of 34 eyes (41.2%) with anterior zone I ROP and 6 out of 6 (100%) eyes with posterior zone I ROP had unfavorable outcome (p=0.007). In the surgery group 13 out of 17 eyes (76,5%) with stage 4 and 5 out of 11 eyes (45,5%) with stage 5 ROP had a favorable outcome. Conclusion:Laser for Zone I ROP is not as effective as for Zone II. Zone I eyes need earlier treatment. Surgical intervention can effectively attach the retina in some cases of stage 4 and 5 ROP.
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