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S Bueltmann, P Weimer, K Rohrschneider; The Influence of Refractive Errors on mfERG Results . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2011.
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Purpose: To evaluate the influence of refractive errors on results and interpretation of multifocal ERG results. Methods: 10 eyes of 5 normal subjects were examined with the RETIscan/CRT following pupil dilation. We used gold-foil electrodes as well as JET electrodes on a 103 hexagon test pattern for binocular testing. While one eye was optimized for refractive values, the other one was subject to testing with plus-lenses as well as cylinders up to 6dpt. After this, the refractive values were exchanged between the two eyes and retested. Objective refraction with JET electrodes was performed by retinoscopy. Results: While good results with central fixation were recorded in the control eyes, the artificial spherically myopic eyes showed a shift of fixation according to the pupillary distance (2 hexagons -70 mm). Astigmatic misrefraction resulted in less stable central fixation leading to a shift of P1 amplitudes from the center into periphery. We found a change in refraction for the JET electrodes that may also influence results. Conclusion: Assessment of good refractive values is important especially for binocular testing. This allows the best possible conditions for stable fixation when patients with central pathologies need to be diagnosed. Incorrect refractive compensation may lead to false results in healthy eyes and should be taken into account when the results are evaluated. Refractive values of JET electrodes may vary and are harder to measure with some common autorefractors.
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