December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Brimonidine Tartrate Ophthalmic Solution 0.2% Effectively Reduces Postoperative Halo in LASIK Patients
Author Affiliations & Notes
  • C-M Choe
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • I-S Lee
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • G-O Kim
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • H-I Kim
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • K-S Lee
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • Y-S You
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • J-K Kim
    Refractive Surgery ALC eye clinic Seoul Republic of Korea
  • Footnotes
    Commercial Relationships   C. Choe, None; I. Lee, None; G. Kim, None; H. Kim, None; K. Lee, None; Y. You, None; J. Kim, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 2111. doi:
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      C-M Choe, I-S Lee, G-O Kim, H-I Kim, K-S Lee, Y-S You, J-K Kim; Brimonidine Tartrate Ophthalmic Solution 0.2% Effectively Reduces Postoperative Halo in LASIK Patients . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2111.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose:To evaluate the effect of brimonidine tartrate(Alphagan) on halo and pupil size in LASIK patients. Methods:14 LASIK patients with symptomatic night vision difficulties where enrolled in our study. Pupil size was checked with Colvard pupillometer and quantitative analysis of post-operative halo was done with a new computerized method. Both pupil size and halo were checked under 2 luminance conditions, scotopic and normal room light. Alphagan was administered to each patients and effect was measured after 30minutes, 1, 6, 12, and 24 hours. Results:Both pupil size and halo size decreased significantly after 30 minutes and lasted until 12 hours after Alphagan instillation(p<0.05). Mean halo size before Alphagan administration were 1688 and 2459 under normal room and scotopic conditions, respectively. 6 hours after alphagan administration halo size were reduced to 31% and 35% in room and scotopic lumination, respectively. Halo size return to 67% and 71% of the original size after 24 hours. Conclusion:Brimonidine tartrate effectively reduces halo and pupil size in lasik patients with symptoms of night vision problems.

Keywords: 548 refractive surgery: LASIK • 545 refractive surgery: complications • 546 refractive surgery: comparative studies 
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