Abstract
Abstract: :
Purpose: To determine the prevalence of Short Wavelength Automated Perimetry (SWAP) deficits at baseline for patients enrolled in the Ocular Hypertension Treatment Study (OHTS), to compare prevalence of baseline deficits by SWAP and standard automated perimetry, and to evaluate the relationship between SWAP results and other baseline clinical characteristics of the OHTS patients. Methods: SWAP testing was performed in 397 eyes of 199 patients enrolled in the OHTS SWAP ancillary study at nine participating clinical centers, using the previously-determined optimal testing conditions for SWAP. A standardized protocol was used for all clinical centers and all technicians were certified prior to testing patients. Results: At baseline, the prevalence of SWAP abnormalities for the Glaucoma Hemifield Test (GHT) analysis was approximately 20.9%. There was a statistically significantly higher prevalence of SWAP abnormalities in African American patients (32.6%) as compared to Caucasians (19.2%), and for patients with a high school education or less (31.6%) as compared to patients with 1 or more years of college (19.1%). No other statistically significant associations were found for the prevalence of SWAP deficits as a function of age, gender, intraocular pressure (IOP), diabetes, high blood pressure, low blood pressure, family history of glaucoma or migraine. Conclusions: Approximately 20% of OHTS patients enrolled in the SWAP ancillary study demonstrated abnormalities on the SWAP GHT analysis, despite having repeatedly normal and reliable baseline visual fields on standard automated perimetry. Our results suggest that the prevalence of SWAP deficits is significantly higher in African Americans and in patients with a lower education level. NIH/NEI Grants EY-03424, EY-11154, EY-08208
Keywords: 511 perimetry • 624 visual fields • 362 color vision