Abstract
Abstract: :
Purpose: To analyze the longterm survey of chlamydial conjunctivitis, either neonatal chlamydial conjunctivitis or afult inclusion conjunctivitis, in one eye clinic in Sapporo, Japan. Methods: A total of 151 cases of chlamydial conjunctivitis, diagnosed by chlamydial isolation, immunohistochemistry and immunoperoxidase antibody methods, were analyzed in terms of the yearly occurrence of chlamydial conjunctivitis from 1983 to 2000. Serotyping were performed in 30 cases and four sex partners using by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. Results: 1) The incidence of chlamydial conjunctivitis was at the peak in 1985, and thereafter gradually decreased in number. 2) Neonatal chlamydial conjunctivitis were frequently found until 1988, however since then it gradually decreased in number and there was no cases seen after 1996. 3) Serotype analysis of 30 cases revealed that serotype D was seen in 7 cases, E was 9, F was 3, G was 5, H was 5 and K was 1. There was no cases with serotype I or J. 4) Serotype analysis in four cases with sex partners showed the same serotypes between them. Conclusion: Gynecologic or urological treatment against chlamydial infection seems to contribute the decreased incidence of chlamydial conjunctivitis in Sapporo, Japan.
Keywords: 602 trachoma • 366 conjunctivitis • 476 molecular biology