Abstract
Abstract: :
Purpose: To report the anatomical and functional outcome of macular hole surgery with internal limiting membrane (ILM) peeling and injection of long-acting gas (C3F8) Methods: We examined prospectively 40 eyes of 40 patients with idiopathic macular hole undergoing vitrectomy, ILM-peeling and fluid-gas exchange and compared the best-corrected visual acuity levels with postoperative features of optical coherence tomography and scanning laser ophthalmoscopy images. Results:The treatment was anatomically successful in 30 of 40 eyes (75%) and 17 of the eyes (42,5%) showed an improvement of at least two Snellen lines. The mean of the retinal thickness was 424 nm (range 300-600nm) preoperatively. Postoperatively the mean of the retinal thickness decreased to 348 nm (range 250-370 nm) in cases with anatomical success (P=0,008, Student t-test). In cases of macular hole closure the mean of the foveal thickness ranged from 80 to 440 nm (the mean 180 nm). In all tested eyes fixation-point was preoperatively paracentral. Postoperatively the fixation-point was central in 62,5%, and paracentral in 37,5%. Conclusion:Successfull closure of macular holes was achieved in 75% of the cases. Tomographic images after macular hole surgery correlated with functional outcomes such as best-corrected visual acuity levels and fixation-point.
Keywords: 461 macular holes • 357 clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)