Abstract
Abstract: :
Purpose: Enhance anatomic detailing of the coats of the posterior pole of the eye. Methods: Concurrent OCT Slit Lamp images were used for localization of subsequent ultrasound images. Grey scale OCT images and deconvolved, de-noised analytic magnitude high frequency ultrasound B-scans (15-25 MHz) were reformatted and interpolated to a common geometric space. Image co-registration was performed using the apical RPE and image segment boundaries as fiducial markers along with affine transformation using multi-variate minimization. Information fusion with multi-resolution and Bayesian optimization methods was then performed. Results: In a series of patients, good empirical matches can be made between OCT and US in co-localization of the ILM and apical RPE. Combined OCT and US images provide improved resolution of retinal layers and better definition of the choroid in a single image. Conclusion: Enhanced details with two-dimensional data acquisition imaging improves selection and evaluation of disease states, as well as of the effects of treatment modalities, such as laser or systemic medication.
Keywords: 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 554 retina