Abstract
Abstract: :
Purpose:To establish normal ranges of thickness of various retinal regions in healthy subjects with different degrees of ametropia when using Optical Coherence Tomography (OCT). Methods:Thirty-six healthy normal subjects, ages 20 to 83 years (48 18 years) were recruited. All subjects had a complete ophthalmologic exam. Their refractive error (spherical equivalent) varied from -14 to + 4 diopters. The ocular axial length was measured with A-scan ultrasonography. The axial length of the eyes ranged from 21.7 to 26.4 mm. OCT was used to measure the retinal thickness in 3 locations of one eye in each subject: macula (including fovea), peripapillary retina, and retina 6 mm temporal to the fovea. Results:Average retinal thickness by OCT in emmetropic eyes was 256, 233 and 201 um for peripapillary retina, macula and temporal retina, respectively. Average thickness in hyperopic eyes was 262, 227 and 182 um for peripapillary retina, macula and temporal retina, respectively. Average thickness in myopic eyes was 246, 224 and 181 um for peripapillary retina, macula and temporal retina, respectively. The thickness in the peripapillary, macular or temporal retina was not significantly correlated with the axial length or refractive power of the eye. A lack of statistically significant difference between the average thicknesses in the hyperopic, emmetropic, and myopic eyes was found. Conclusion:The average thickness by OCT measurement in the peripapillary retina, macula and posterior temporal retina was not influenced by either axial length or refractive status of the eye.
Keywords: 430 imaging/image analysis: clinical • 481 myopia • 427 hyperopia