Abstract
Abstract: :
Purpose:To investigate retinal hemodynamic and electroretinographic changes with laser irradiation around the stellate ganglion Methods:Low reactive-level laser irradiation for 7 minutes near the stellate ganglions bilaterally were underwent in 15 healthy volunteers (7 males, 8 females; mean age: 27.6 years). Confocal scanning laser doppler flowmetry (LDF) and multifocal electroretinograms (MERG) were performed before and 1 hour after laser irradiation. The mean of blood volume, velocity, and flow obtained from three temporal peripapillary sites in an LDF image were calculated with a 10Å∼10 pixel frame and analyzed. The stimulus for MERG was composed of 19 hexagons and the signal was amplified through 10-100 Hz bandpass-filter for recording MERGs. The amplitudes and implicit times of the first negative (N1) and positive (P1) waves in all traces were measured and analyzed. Results:The laser irradiation increased the flow and velocity of retinal capillary by 32.0Åì and 30.3Åì at 1 hour after irradiation, respectively. There was a significant difference in the flow and the velocity between pre-and post-laser irradiation (P<0.05). MERG results showed a significantly increase in the N1 and P1 amplitude (P<0.05), but no difference in the N1 and P1 latency between pre-and post-laser irradiation. Conclusion:The laser irradiation around the stellate ganglion showed the increase of retinal capillary flow and retinal neural activity. This non-invasive method could be one of the useful treatment for acute or chronic retinal blood circular disturbances.