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MR Melson, C Servodidio, DH Abramson; Visual Fields in Successfully Treated Retinoblastoma Patients . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2589.
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Purpose: To describe the visual field defects in retinoblastoma survivors and relate those defects to characteristics such as tumor size, tumor location, and treatment modality. Method: Thirty-one retinoblastoma patients treated at the Ophthalmic Oncology Center at New York Presbyterian Hospital, New York Weill Cornell Medical Center were included in this study. Humphrey's Visual Fields were performed on 33 eyes in all 31 patients. Results: Twenty-seven patients (29 eyes, 68 tumors) had sufficient diagnosis and treatment data available for further analysis. Twenty-six of the 27 patients had both absolute and relative visual field defects. Twenty patients had defects within the central 30 degrees of the visual field. Nineteen patients had defects within the peripheral 30-60 degrees. Sixteen patients had defects in both the central 30 degrees and peripheral 30-60 degrees. Twenty tumors produced defects that were larger than predicted based on tumor size alone. Nineteen patients had an enlarged brow/nose defect. An enlarged brow/nose defect was defined as a nasal defect extending greater than 10 degrees nasally and a superior defect extending greater than 20 degrees superiorly. All 27 patients had either absolute or relative defects that crossed the vertical meridian. Twenty-three of the 27 patients had defects that crossed the horizontal meridian. Four patients had an arcuate visual field defect. Conclusion: Retinoblastoma patients demonstrate a variety of long-term visual field defects following treatment for their primary disease. Characteristics that determine the size and type of defects are tumor size, tumor location, and treatment method.
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