December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Photophobia:: A light induced Ocular Pain. Is It the Third Pathway for Light Perception?
Author Affiliations & Notes
  • V Scorcia
    Ophthalmology Università degli studi di Catanzaro Magna Graecia Catanzaro Italy
  • G Scorcia
    catanzaro Italy
  • F Scarinci
    catanzaro Italy
  • M Fratto
    catanzaro Italy
  • G Carnovale-Scalzo
    catanzaro Italy
  • V Piccirillo
    catanzaro Italy
  • D Richichi
    catanzaro Italy
  • J Feher
    catanzaro Italy
  • Footnotes
    Commercial Relationships   V. Scorcia, None; G. Scorcia , None; F. Scarinci , None; M. Fratto , None; G. Carnovale-Scalzo , None; V. Piccirillo , None; D. Richichi , None; J. Feher , None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 2644. doi:
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      V Scorcia, G Scorcia, F Scarinci, M Fratto, G Carnovale-Scalzo, V Piccirillo, D Richichi, J Feher; Photophobia:: A light induced Ocular Pain. Is It the Third Pathway for Light Perception? . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2644.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose:Light induced pain is a common symptom of several inflammatory eye diseases affecting either the anterior or posterior segment. However, it may also occur in some chorioretinal degenerations, and the pathomechanism of photophobia is poorly understood in these conditions. The aim of our studies was to reveal the association of photophobia with chorioretinal degenerations and to learn more on the pathophysiology of photophobia Methods:During a year of period all out patients visited our department were evaluated by questioner about photophobia and associated eye conditions Results:Approximately one fifth of our out patients referred various degree of photophobia almost always as a secondary symptom. Most of them were affected by uveal or corneal inflammation. Ocular surface inflammations ("dry eye") were also always associated with various degree of photophobia. The rest of the photophobia patients were affected by posterior pole degeneration (55%), peripheral retinal dystrophy (35%), and approximately 10% of the photophobia cases were no ocular disease but almost all suffered from headache, mostly migraine. These latter reported photophobia even between migraine attack Conclusion:Photophobia is a common subjective symptom which may call ophthalmologist's attention to "silent" but potentially harmful retinal diseases. While corneal and uveal inflammation may cause hyperalgesia in the ciliary body, in cases of chorioretinal degenerations the choroidal sensory nerve involvement seems to be responsible for the photophobia. These observations suggested that, besides visual and retino-hypothalamic pathways, choroidal sensory nerves may also contribute the light "perception".

Keywords: 559 retinal connections, networks, circuitry • 437 inflammation • 556 retina: neurochemistry 

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