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RA Yee Chan, MP Hernandez; Incidence and Clinical Presentation of Adie's Tonic Pupil Syndrome: Half-decade Experience . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2647.
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Purpose:To evaluate the incidence and the variables in the clinical presentation of the Adie's Tonic Pupil Syndrome (ATPS) at the hospital. Methods: Retrospective review of 23 patients with ATPS diagnosis over a period of 5 years. Results: A total of 23 cases were reviewed. Thirteen cases of ATPS were identified in the period between 1995-2000. The incidence of ATPS was 0.005% of the total hospital population. Twelve patients were female (98%) and one patient (2%) male, with an age range of 10 to 45 years and a mean age of 25 years. All cases had a tonic pupil with anisocoria due to unilateral relative mydriasis in bright illumination, with poor to absent light reaction, slow pupil contraction to prolonged near-effort and a slow redilation after near-effort. One patient referred periorbital pain. In all cases there was no evidence of morphological anomalies, nystagmus, eyelid or extraocular muscle dysfunction. Conclusion: All of the patients had a tonic pupil with anisocoria due to unilateral relative mydriasis. It's essential to follow up this patients in order to find a cause since the etiology of this syndrome is still unknown.
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