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SH Hahn, SP Azen, M Lai, R Varma; Central Corneal Thickness (CCT) in Latinos with Ocular Hypertension: The Los Angeles Latino Eye Study (LALES) . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2945.
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Purpose: To determine the relationship between CCT and various ocular factors, in a population of Latinos, aged 40 years and older with IOP ≷ 21 mm Hg. Methods: A population-based sample of Latinos underwent a complete ophthalmic examination including measurement of IOP, CCT, refractive error and axial length . Three measurements of CCT and axial length were obtained using an ultrasonic A-scan pachymeter. Three measurements of IOP were obtained by applanation using a Goldmann tonometer. In this analysis, we include participants whose IOP was ≷ 21 mm Hg. The relationship between CCT and age, IOP, refractive error, axial length, was studied using ANOVA, t-tests and linear regression analysis. Results: 184 eyes from 184 participants with IOP ≷ 21 mm Hg were included. 113 (61%) were females. The mean + SD age was 59+ 10 years. The mean CCT, IOP and axial length were: 562 mm , 22.9 mm Hg, and 23.2 mm, respectively. The mean CCT among different age groups was: 40-49 years: 570 mm; 50-59 years: 567mm; 60-69 years: 556mm and 70 and older: 549mm. Statistical analyses revealed a significant correlation between CCT and age (p=0.005). CCT in individuals 70 and older was significantly thinner when compared to individuals 40-49 years of age (p=0.01) and 50-59 years of age (p=0.02). There was no statistically significant association between CCT by gender, (p=0.7), IOP, axial length and refractive error (p=0.86). Conclusions: In this population-based sample of Latinos with IOP ³ 21 mm Hg, CCT was thinner in older individuals compared to younger individuals. Also, IOP was not associated with differences in CCT
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