December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Four-Year Incidence of "High" Intraocular Pressure and Related Factors - The Barbados Eye Studies
Author Affiliations & Notes
  • BB Nemesure
    School of Medicine Stony Brook University Stony Brook NY
  • SY Wu
    School of Medicine Stony Brook University Stony Brook NY
  • A Hennis
    Ministry of Health and University of the West Indies Bridgetown Barbados
  • MC LeskeBarbados Eye Studies Group
    School of Medicine Stony Brook University Stony Brook NY
  • Footnotes
    Commercial Relationships   B.B. Nemesure, None; S.Y. Wu, None; A. Hennis, None; M.C. Leske, None. Grant Identification: NIH Grant EY07625 and NIH Grant EY07617
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 2946. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      BB Nemesure, SY Wu, A Hennis, MC LeskeBarbados Eye Studies Group; Four-Year Incidence of "High" Intraocular Pressure and Related Factors - The Barbados Eye Studies . Invest. Ophthalmol. Vis. Sci. 2002;43(13):2946.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Abstract: : Purpose: To evaluate the 4-year incidence of elevated intraocular pressure (IOP) and associated factors in a predominantly black population. Methods: This report is based on 3427 (85% of those eligible) Barbados Incidence Study of Eye Disease (BISED) participants who were re-examined four years after their baseline visit. Incidence of elevated IOP was determined at various cutoff values, after excluding individuals with baseline IOP≷21mmHg/treatment or any glaucoma diagnosis. Associations of high IOP with possible risk factors were evaluated using polychotomous logistic regression. Results: At baseline, 2495 black participants had IOP ≤21 mmHg and no glaucoma. Using a cutoff of IOP≷21 mmHg (representing the 80th percentile in this population) at baseline, the 4-year incidence of "high" IOP (not attributable to glaucoma) among this group was 12.9% (95% confidence interval (11.7%, 14.3%)). For IOP≷24 mmHg (90th percentile), incidence was 5.8% (4.9%, 6.8%); and for IOP≷28 mmHg (95th percentile) incidence was 1.8% (1.3%, 2.4%). Factors associated with high IOP included older age, higher baseline IOP, hypertension, systolic (SBP) and diastolic blood pressure (DBP). Although persons with 21<IOP≤28 mmHg tended to have higher SBP (medians from 140-141 mmHg) and DBP (medians from 82-85 mmHg), those with IOP≤21 mmHg and IOP≷28 mmHg had lower BP values (median SBP and DBP of 129/80 and 129/78 mmHg, respectively). Conclusion: Given the IOP distribution in this Afro-Caribbean population, definition of "high" IOP may be more relevant if based on cut-offs representing the 90th-95th percentiles rather than if based on arbitrary values. Older individuals and those with higher baseline IOP were more likely to develop elevated IOP after four years. Although BP was associated with elevated IOP, the relationship may not be linear and requires further investigation.

Keywords: 354 clinical (human) or epidemiologic studies: prevalence/incidence • 355 clinical (human) or epidemiologic studies: risk factor assessment • 444 intraocular pressure 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.