Abstract
Abstract: :
Purpose: The neonatal anophthalmic socket is at risk of bony and soft tissue maldevelopment. We evaluated the benefit of progressive custom fit conformers in the development of the neonatal porcine anophthalmic orbit. Methods: Six Yorkshire piglets underwent enucleation of the right eye at five days of life. A custom conformer was fit for the anophthalmic socket. At two-month intervals until the sixth month of life, CT Scans of the bony orbits were obtained. At each interval, a new custom fit conformer was created for the anophthalmic socket. Results:At two months, the anophthalmic orbits averaged 20.2% smaller than the control orbits. At four months, the anophthalmic orbits averaged 22.1% smaller than the control orbits. And at six months, the anophthalmic orbits averaged 23.4% smaller than the control orbits. Conclusion: While assisting in soft tissue enlargement, custom fit conformers provided limited stimulation of bony orbital growth in this porcine population.
Keywords: 315 anatomy • 432 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 316 animal model