Abstract
Abstract: :
Purpose:To investigate the characteristic of anterior eye segment structure in Cornea guttata (CG) in Japanese population by Scheimpflug photography. Methods:Among the 1485 participants over 50 years of age of the population based study carried out in Noto, Japan,51 eyes of 32 subjects (1997-2000) with CG (Mean age 65±7yrs, Males 18.8%)were selected. Definition of CG were done by single observer both with slitlamp and specular microsopy (Noncon ROBO,Konan). 195 cases(Mean age 64±7yrs, Male 32.8%)from the study were selected as age adjusted controls. Scheimpflug images of the anterior segment were documented with a anterior eye segment analysis system (EAS-1000, NIDEK) under undilated and maximally dilated pupils. Anterior camber depth (ACD), lens thickness (LT) and chamber angle (CA) were measured from the photographed images. The distance from the anterior capsule to the central clear zone was used to indicate LT in this study. Results:Prevalence of CG was 1.7% (0.6% in males and 2.6% in females). Prevalence of CG was significantly higher in females in all the age groups. ACD and CA were 2.44±0.37mm and 20.0±5.4° in CG and 2.68±0.12mm and 22.45±6.1° in control. No significant difference was seen in LTs between both groups. Conclusion:In Japanese population, ACD was shallower and CA was narrower in CG subjects. These results indicate that CG subjects are at a higher risk for the development of Primary angle closure glaucoma.
Keywords: 318 anterior segment • 371 cornea: endothelium • 350 clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology