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M Scibor, G Michelson, H Wenkel, J Harazny, D Schweitzer, M Hammer; Measurement Of Retinal And Systemic Oxygen Saturation In Normals And Patients With Venous Retinal Occlusion . Invest. Ophthalmol. Vis. Sci. 2002;43(13):3305.
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Purpose: to measure oxygen saturation in retinal arterioles and retinal venoles and capillary systemic oxygen saturation in normals and patients with venous retinal occlusion. Methods: The determination of capillary systemic oxygen saturation was performed with blood gas analyser Radiometer ABL 510. The determination of retinal oxygen saturation was performed using the Imaging Spectrometer, developed in Jena. The basis for the non-invasive estimation of the oxygen saturation is different extinction spectra of hemoglobin and oxyhemoglobin. The measurements of the reflectance spectra were performed in a wavelength range from 400 nm to 700 nm. The retinal oxygen saturation was measured with an entrance slit of 1.5 mm, spectral resolution of Δ;λ < 2m, and local resolution Δ;s < 7.8µm.We measured 58 eyes of 42 healthy persons and 12 eyes of 12 patients with retinal vein occlusion. Results: In normals the oxygen saturation was in average 91%+-5% in retinal arterioles and 57% +-8% in retinal venoles.In patients with venous retinal occlusion the oxygen saturation was in average 88% +-5% in retinal arterioles and 29% +-12% in retinal veins.The capillary systemic oxygen saturation in patients with venous retinal occlusion was in avarage 95%+-3%. Conclusions: In eyes with venous retinal occlusion we found a significant decrease of local oxygen saturation in retinal veins and retinal arterioles. In the systemic capillary oxygen saturation we found no significant difference between normals and patients with venous retinal occlusion.
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