Abstract
Abstract: :
Purpose: To create an implant that will drainage excess of intraocular fluid from the eye and maintain the intraocular pressure within normal range. Methods: A specially designed implant was implanted in normal and glaucomatous born laboratory rabbits. The site of implantation was the corneal limbus.The surgery was done according to the Animal Care Guide Lines.Intraocular pressure was measured daily for one week following surgery and weekly for the following period up to six months.The implanted eyes were examined at slit lamp for evaluation of any sign of inflammation and other possibble complication due to surgery. Results: In a total of ten rabbits, no one of the implants was rejected or expulsed.No inflammatory reaction was observed in any of the eyes.The intraocular pressure was lower in the implanted eye compared with the contralateral non implanted eye. Statistical analyisis of the data showed significant difference between the implanted and non implanted eyes as regarding the IOP. Conclusion: Our new glaucoma implant, which is small and easy to be manipulated in a simple surgery , presents positive results in our pilot study.
Keywords: 444 intraocular pressure • 316 animal model • 324 aqueous