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CP Arroyave, IU Scott, RK Parrish II, SJ Gedde, W Feuer; Glaucoma Drainage Devices in Eyes With Glaucoma Associated With Aniridia . Invest. Ophthalmol. Vis. Sci. 2002;43(13):3359.
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Purpose: To investigate visual acuity and intraocular pressure outcomes, as well as complications, following glaucoma drainage device placement (GDD) in eyes with glaucoma associated with aniridia. Methods: The medical records of all patients who underwent GDD placement for the management of glaucoma associated with aniridia at Bascom Palmer Eye Institute between January 1, 1989 and December 31, 1999 were reviewed. Results: The study included 8 eyes of 5 patients with a median age at the time of GDD placement of 14 years ( range 10 months to 41 years). Patients were followed a median of 22 months postoperatively. Two eyes had undergone multiple glaucoma surgeries prior to GDD placement. Eleven months after GDD placement, one eye developed a rhegmatogenous retinal detachment and became phthisical. despite of treatment. The remaining 7 eyes had a mean decrease in intraocular pressure of 19+12 mm Hg (p=0.005, paired t- test) with IOP less than 21 mm Hg without complications at last follow-up. Kaplan-Meier cumulative survival percentages for IOP less of 21 mm Hg were 100% at 6 months, 88%+12% at one year and thereafter. Final vision was stable compared to preoperatively in 5 eyes (62%) and improved in 2 (25%). Conclusions: GDD placement for glaucoma associated with aniridia achieves IOP control and vision preservation in most patients.
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