December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Retinal Involvement in Type 2 Diabetics with Microalbuminuria
Author Affiliations & Notes
  • R Bigioni
    Institute of Ophthalmology University La Sapienza Rome Rome Italy
  • F Gentile
    University of rome "la sapienza"
    institute of ophthalmology Institute of ophthalmology Italy
  • L Carlomusto
    University of rome "la sapienza"
    institute of ophthalmology Institute of ophthalmology Italy
  • EM Vingolo
    University of rome
    institute of ophthalmology Institute of ophthalmology Italy
  • Footnotes
    Commercial Relationships   R. Bigioni, None; F. Gentile, None; L. Carlomusto, None; E.M. Vingolo, None. Grant Identification: MD
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 3475. doi:
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    • Get Citation

      R Bigioni, F Gentile, L Carlomusto, EM Vingolo; Retinal Involvement in Type 2 Diabetics with Microalbuminuria . Invest. Ophthalmol. Vis. Sci. 2002;43(13):3475.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: In patients with type 2 diabetes, the presence of microalbuminuria, reflecting a widespread vascular damage, can be a marker of nephropathy, retinophaty and cardiovascular diseases. AIM: To study the relationship between microalbuminuria and the frequency, severity and outcome of retinopathy in patients with type 2 diabetes mellitus Methods: One hundred patients with type 2 diabetes were subjected to a clinical examination, and measurement of microalbuminuria by RIA. Twice a year, a fundoscopy, a color photography of the posterior pole and retinal angiofluorescence were performed. Retinopathy was classified as basal (mild to moderate), preproliferative and proliferative. Sixty-four normoalbuminuric patients (urinary albumin of less than 30 mg/24 h) were included in group 1 and 36 patients with a urinary albumin over 30 mg/24 h in group 2. Results: Sixty one percent of group 1 patients and 41% of group 2 patients has retinopathy (p < 0.05). The retinal lesions were proliferative in 41% of group 2 patients and in 8% of group 1 patient (p < 0.05). An unfavorable evolution of retinopathy was observed in 22% of group 2 patients and in 5% of group 1 patient (p < 0.05). Conclusion: In type 2 diabetic patients, the presence of microalbuminuria is a prediction of a higher frequency, severity and dismal evolution of diabetic retinopathy.

Keywords: 387 diabetes • 554 retina • 388 diabetic retinopathy 
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