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A Majji, VA Shah, GK Vemuganti, S Singh, TP Das, S Jalali; Morphological Evaluation of Epiretinal Membranes . Invest. Ophthalmol. Vis. Sci. 2002;43(13):3517.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study the histopathologic characteristics of epiretinal membranes (ERM) obtained during vitrectomy and to correlate the observations to clinical relevance. Methods: Clinical records of 40 patients with ERM from 1995 to 2000 were reviewed. Demographics, preoperative & postoperative vision, location & type of membranes were studied. Histopathologic features were correlated with clinical parameters. The results were analyzed statistically. Results: The clinical diagnoses included Diabetes (27.5%), Eales (25%), Trauma (15%), Branch vein occlusion (10%) & Retinal Detachment (10%). The type of membranes were fibrous (50%), Vascular (20%), Fibrovascular (20%) and inflammatory (15%). Fibrovascular membranes were associated with better vision (P=0.033). Membrane peeling improved vision in most subgroups, except in trauma (P=0.018). Conclusion: Histological features of ERM aid in prognosticating visual outcome. Larger number of cases with long follow-up are required to draw more definite conclusions.
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