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JW Kitchens, KT Oh, hC Boldt, JC Folk; Intraocular Steroids for the Complications of Posterior Uveitis . Invest. Ophthalmol. Vis. Sci. 2002;43(13):3974.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To report the results of a series of patients who were treated with intravitreal steroids for the complications of posterior uveitis. Methods: Retrospective descriptive case series. Six patients with posterior uveitis from various etiologies underwent at least one intravitreal treatment with either 4 mg triamcinolone acetonide or 500 mcg dexamethasone. Diagnoses inculded multifocal choroiditis, panuveitis and diffuse subretinal fibrosis (3), serpiginous choroidopathy (1), sympathetic ophthalmia (1), and phacoantigenic uveitis (1). In three cases, recurrent inflammation was noted prior to treatment despite maximal medical therapy with systemic and sub-Tenon's steroids and immunosuppressive agents. Results: Follow-up ranged from three to nine months (median: six months) following treatment. Five patients received intravitreal triamcinolone acetonide and one received intravitreal dexamethasone. Three of the six patients underwent multiple injections. Two patients demonstrated choroidal neovascularization associated with the uveitis while the remaining four demonstrated inflammatory changes secondary to their active uveitis. Improvement in inflammation and/or reduction of the choroidal neovascular membrane was observed in all six of the patients following treatment. Visual improvement was observed in five patients. Four of the six patients developed mild ocular hypertension. Conclusion: Intravitreal steroids provide an effective alternative in the management of patients with posterior uveitis.
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