December 2002
Volume 43, Issue 13
Free
ARVO Annual Meeting Abstract  |   December 2002
Strict Oxygen Management is Associated with Decreased Incidence of Severe of Retinopathy of Prematurity
Author Affiliations & Notes
  • PH Hong
    Ophthalmology
    Cedars-Sinai Medical Center Los Angeles CA
  • KW Wright
    Ophthalmology
    Cedars-Sinai Medical Center Los Angeles CA
  • S Fillafer
    Neonatology
    Cedars-Sinai Medical Center Los Angeles CA
  • A Sola
    Neonatology Emory University Atlanta GA
  • LC Chow
    Neonatology
    Cedars-Sinai Medical Center Los Angeles CA
  • Footnotes
    Commercial Relationships   P.H. Hong, None; K.W. Wright, None; S. Fillafer, None; A. Sola, None; L.C. Chow, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 4011. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      PH Hong, KW Wright, S Fillafer, A Sola, LC Chow; Strict Oxygen Management is Associated with Decreased Incidence of Severe of Retinopathy of Prematurity . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4011.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: To determine whether strict curtailment of oxygen in the neonatal intensive care unit (NICU) is associated with decreased levels of severe retinopathy of prematurity (ROP). Methods: This was a retrospective longitudinal study of the incidence of severe ROP in infants <1501g birthweight before and after implementation in April 1998 of a new clinical practice of oxygen management in a large level III NICU. Data was collected in real time in a local database. A separate phase of the study included a retrospective chart review of the incidence of myopia and strabismus in infants <1251g birthweight who underwent strict oxygen monitoring. Results: The incidence of stage III-IV ROP significantly decreased from 12.0% in 1997 (n=217) to 2.3% in 2000 (n=260) (p<0.01). The need for ROP laser treatment decreased from 4.6% in 1997 to 0% from 1999-2000 (p<0.01). The incidence of stage III-IV ROP and ROP laser as reported by the Vermont Oxford Network had not changed significantly over the same time period. The prevalence of -0.25 D or greater myopia was 7.5% (6/80) in eyes with 3-12 months post-term follow-up and 25.8% (16/62) in eyes with 1-3 years post-term follow-up. The prevalence of strabismus was 10.0% (4/40) in patients with 3-12 months post-term follow-up and 19.4% (6/31) in patients with 1-3 years post-term follow-up. Conclusion: Severe ROP in very low birthweight infants has decreased significantly in association with the implementation of a strict bedside practice of oxygen management. The prevalence of myopia and strabismus in our study group was similar to previous reports for very low birthweight infants at other centers. CR: None. Support: The Discovery Fund for Eye Research, The Henry L. Guenther Foundation, The Pfeiffer Foundation, Ruth and Harry Roman Chair in Neonatology - Cedars-Sinai Medical Center

Keywords: 572 retinopathy of prematurity • 588 strabismus • 481 myopia 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×