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H Specht, HE Voelcker, FE Kruse; A New Fiber Optic Device for Non Mechanical Trephination with the 308 nm Excimer Laser . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4171.
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Purpose: Compared to mechanical methods, Excimer laser trephination for penetrating keratoplasty offers distinct advantages. However due to very demanding technical requirements the use of this method is currently limited to a few centers. Here we describe a simple trephine which can be used in conjunction with small, mobile, laser units. Methods: A motor driven trephine was developed which can be centered by use of a suction ring. It is used in conjunction with a fiber that is connected to a small, mobile, commercially available 308nm Excimer laser. In a pre clinical study freshly enucleated pig an human eyes were used. Conventional histology war performed following trephination with the Excimer laser trephine. Results: The laser trephine was reliably attached to the ocular surface by use of the suction ring. Both human and porcine corneas could be cut with a diameter up to 12 mm. Trephination stopped when aqueous humor penetrated through the wound. Histology showed smooth cutting edges and a zone of thermal damage that measured less than 10 micron. Conclusion: The new laser trephine system offers advantages over the current method of Excimer laser trephination and its practicability should allow widespread clinical use.
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