Purchase this article with an account.
MS Benz, IU Scott, HW Flynn, D Miller; In Vitro Susceptibilities to Antimicrobials of Pathogens Isolated from the Vitreous Cavity of Patients with Endophthalmitis . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4428.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate the spectrum of organisms causing culture-proven endophthalmitis and their sensitivities to commonly used antimicrobial agents. Methods: Medical records were reviewed of all patients with culture-proven endophthalmitis at a single institution between January 1, 1996 and December 31,2000. Results: 260 organisms were isolated from 230 patients during the study interval. Staphylococcus epidermidis (71/260;27%), Streptococcus viridans group (37/260;15%), and coagulase-negative staphylococci (26/260;10%) were found to be the most common infecting microbes. Overall, 211 of 260 (81%) of cases were caused by gram-positive organisms, 32 of 260 (13%) by gram-negative organisms, and 14 of 260 (5%) by fungi. Of gram-positive organisms, 100% were sensitive to vancomycin, 75% were sensitive to gentamicin, 70% were sensitive to ciprofloxacin, and 40% were sensitive to penicillin. Of gram-negative organisms, 70% were sensitive to gentamicin and 92% were sensitive to ciprofloxacin. Conclusion: No single antibiotic provided coverage for all of the microbes isolated from eyes with endophthalmitis.
This PDF is available to Subscribers Only