December 2002
Volume 43, Issue 13
ARVO Annual Meeting Abstract  |   December 2002
Retinal Prosthesis: An Electronic Model
Author Affiliations & Notes
  • A Alcala-Delgadillo
    Retina & Vitreous
    Instituto de Oftalmologia Mexico City Mexico
  • L Niño de Rivera
    Posgrado Esime
    Instituto de Oftalmologia Mexico City Mexico
  • F Graue-Wiechers
    Retina & Vitreous
    Instituto de Oftalmologia Mexico City Mexico
  • Footnotes
    Commercial Relationships   A. Alcala-Delgadillo, None; L. Niño de Rivera, None; F. Graue-Wiechers, None.
Investigative Ophthalmology & Visual Science December 2002, Vol.43, 4464. doi:
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      A Alcala-Delgadillo, L Niño de Rivera, F Graue-Wiechers; Retinal Prosthesis: An Electronic Model . Invest. Ophthalmol. Vis. Sci. 2002;43(13):4464.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose:To design an electronic model, using neural networks and microprocessing technology CMOS, for building a retinal prosthesis for intraocular estimulation at RPE. Methods:We designed a silicon retinal microchip; 4mm in diameter, with microholes in the XII,III, VI and IX meridians with microbrushing in the internal fase of 10 microns of diameter each. In the external fase it has a capacity for 10x10 pixels with microphotodiodes. In vitro implantation over retinal mouse slices and electrophysiology observation was made. Results:We were able to obtain a silicon electronic model with terminals in microbrushing form that can touch directly the SPE. With a control light estimulation over the external fase of silicon chip, we obtain a 70% electrophysiology global response in relation to the expected in experimental models of retinal mouse slices. Conclusion:This electronic model for retinal prosthesis with direct celular estimulation produce an augmentation of the electrophysiology response in the RPE

Keywords: 559 retinal connections, networks, circuitry • 554 retina • 394 electrophysiology: non-clinical 

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