Images obtained from 44 eyes from 44 patients (16 men and 28 women; mean age: 67.7 ± 7.6 years) and 35 normal eyes of 35 subjects (13 men and 22 women; mean age: 69.8 ± 8.1 years) were suitable for analysis in this study.
Table 1 summarizes patients' characteristics prior to surgery. Mean preoperative logMAR BCVA was 0.278 ± 0.204, and mean symptom duration was 20.6 months. In eyes with ERM, mean ONL thickness of the fovea was 368 ± 88 μm, and mean OS thickness was 59 ± 10 μm, both of which were significantly greater than in normal eyes (
P < 0.0001 and
P = 0.0441, respectively). In six eyes, inner retinal layers were included in foveal ONL measurements because of structural continuum of the inner retinal layers.
22 Mean disrupted IZ diameter was 357 ± 176 μm. Mean photoreceptor deformation index was significantly higher in eyes with ERM than in normal eyes (2.66 vs. 0.95, respectively;
P < 0.0001). Photoreceptor deformation index did not significantly correlate with age (
P = 0.6226) and had no association with sex (
P = 0.4366) in normal eyes. Half of the eyes (22 eyes) had cotton-ball sign, a highly reflective foveal region reported by Tsunoda et al.
23 before surgery. The ILM was peeled in 26 eyes, and 0.05% ICG was used to dye ILM in 25 eyes.