October 2015
Volume 56, Issue 11
Erratum  |   October 2015
Investigative Ophthalmology & Visual Science October 2015, Vol.56, 6489. doi:https://doi.org/10.1167/iovs.15-16720a
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      Erratum. Invest. Ophthalmol. Vis. Sci. 2015;56(11):6489. doi: https://doi.org/10.1167/iovs.15-16720a.

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      © ARVO (1962-2015); The Authors (2016-present)

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Erratum in: “Strain and Age Effects on Aqueous Humor Dynamics in the Mouse” by J. Cameron Millar, Tien N. Phan, Iok-Hou Pang, and Abbot F. Clark (Invest Ophthalmol Vis Sci. 2015;56:5764–5776) doi:10.1167/iovs.15-16720 
There were minor labeling errors in Figures 3A and 4, resulting in corresponding errors in the text. 
In Figure 3A, the graphs in the BALB/cJ and C3H/HeJ quadrants were switched. 
In Figure 4, in the BALB/cJ quadrant, the percentage above the Aged column should be ↓80.4%; in the C3H/HeJ quadrant, the percentage above the Aged column should be ↓88.9%. 
In the Results, in the section “Uveoscleral Outflow as Measured Directly via Perfusion of FITC-Dextran (Fu(FITC-dex)),” the second paragraph should read: 
“Fu(FITC-dex) was found to significantly decrease with age in the A/J strain (0.055 ± 0.013 μL/min vs. 0.009 ± 0.002 μL/min, mean Δ = 0.046 μL/min [mean decrease of 83.6%], P < 0.01), in the BALB/cJ strain (0.051 ± 0.018 μL/min vs. 0.010 ± 0.007 μL/min, mean Δ = 0.041 μL/min [mean decrease of 80.4%], P < 0.05), and in the C57-BL/6J strain (0.044 ± 0.012 μL/min vs. 0.006 ± 0.003 μL/min, mean Δ = 0.038 μL/min [mean decrease of 86.4%], P < 0.05; Fig. 4). In the C3H/HeJ strain there was also a decrease but this did not reach statistical significance (0.054 ± 0.020 μL/min vs. 0.006 ± 0.003 μL/min, mean Δ = 0.048 μL/min [mean decrease of 88.9%], P = 0.058).” 
In the same section, the third paragraph should read: 
“Mean values obtained for Fu(FITC-dex) were consistently lower than corresponding mean Fu(calc) values (albeit in different animals) by the following percentages: A/J (Young) Fu(FITC-dex) = 45.83% of Fu(calc); A/J (aged) Fu(FITC-dex) = 25.00% of Fu(calc); BALB/cJ (Young) Fu(FITC-dex) = 77.27% of Fu(calc); BALB/cJ (aged) Fu(FITC-dex) = 90.91% of Fu(calc); C3H/HeJ (Young) Fu(FITC-dex) = 49.54% of Fu(calc); C3H/HeJ (aged) Fu(FITC-dex) = 25.00% of Fu(calc); C57-BL/6J (Young) Fu(FITC-dex) = 55.00% of Fu(calc); C57-BL/6J (aged) Fu(FITC-dex) = 50.00% of Fu(calc).” 
In the Discussion, the first two sentences of the eighth paragraph should read: 
“Results obtained via direct measurement of Fu (Fu(FITC-dex)) using a technique of FITC-dextran perfusion7,54 albeit on different animals, compared favorably with the results obtained for Fu(calc), although mean values for Fu(FITC-dex) were 25% to 90.91% of corresponding mean values for Fu(calc), with five of eight values lying between 45.83% and 77.27%. While the data were not identical, they were within a similar order of magnitude, with absolute values of Fu(FITC-dex) ranging from 0.044 ± 0.012 μL/min to 0.055 ± 0.013 μL/min for young animals, compared with 0.006 ±0.003 μL/min to 0.010 ± 0.007 μL/min for aged animals (representing a reduction with age of 80% to 89%, compared with a reduction with age of 70 to 85% as obtained via Fu(calc)).” 
The article has been corrected online. 
Citation: Millar JC, Phan TN, Pang I-H, Clark AF. Erratum in: Strain and age effects on aqueous humor dynamics in the mouse. Invest Ophthalmol Vis Sci. 2015;56:5764–5776. DOI:10.1167/iovs.15-16720a 

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