In the multivariate analysis, we first dropped from the list of independent parameters refractive error (variance inflation factor [VIF]: 117) and blood concentration of cholesterol (VIF: 7.5). We then deleted parameters that were no longer significantly associated with foveal thickness: depression score (
P = 0.96); age (
P = 0.87); cognitive function score (
P = 0.87); body height (
P = 0.84); body weight (
P = 0.79); level of education (
P = 0.48); anterior corneal curvature radius (
P = 0.57); refractive lens power (
P = 0.59); anterior chamber depth (
P = 0.26); blood concentration of low-density lipoproteins (
P = 0.10); fundus tessellation (
P = 0.19); and optic disc area (
P = 0.10). In the final model, thicker central foveal thickness was associated with male sex (
P < 0.001); urban region of habitation (
P = 0.02); thinner lens thickness (
P = 0.01); thinner subfoveal choroidal thickness (
P = 0.04), and longer axial length (
P < 0.001;
Table 2). If we added presence of epiretinal membranes to the list of independent variables, thicker central foveal thickness remained to be significantly associated with male sex (
P < 0.001; beta: −0.13; B: −5.71; 95% CI: −8.73, −2.69); urban region of habitation (
P = 0.04; beta: 0.07; B: 3.66; 95% CI: 0.19, 7.13); thinner lens thickness (
P = 0.006; beta: −0.11; B: −6.68; 95% CI: −11.0, −2.32); and longer axial length (
P < 0.001; beta: 0.18; B: 3.66; 95% CI: 2.14, 5.19), in addition to the presence of an epiretinal membrane (
P = 0.01; beta: 0.09; B: 12.0; 95% CI: 2.72, 21.3). Subfoveal choroidal thickness was no longer significantly (
P = 0.08) associated with central foveal thickness in that model. If eyes with epiretinal membrane were excluded from the analysis, thicker central foveal thickness was associated with male sex (
P < 0.001), urban region of habitation (
P = 0.04), thinner lens thickness (
P = 0.004), and longer axial length (
P < 0.001), while subfoveal choroidal thickness was not significantly (
P = 0.08) associated with central foveal thickness in that model.