Abstract
Purpose :
To analyze the clinical and morphological characteristics of lamellar macular hole (LMH) associated with two distinctive epiretinal membranes (conventional C-ERM and atypical A-ERM).
Methods :
Observational retrospective study of 189 eyes of 175 patients with LMH. Every cases of LMH presented an epiretinal membrane. The parameters analyzed were: demographic (age, gender, lens status), functional (best corrected visual acuity- BCVA) and tomographic (LMH type, presence of PVD, ERM type, integrity of ellipsoidal line and external limiting membrane, residual foveal thickness and maximal diamete of intraretinal splitting).
Results :
The mean BCVA was better in C-ERM LMH (p<0.001). A significant prevalence of female gender, phakic condition and posterior vitreous detachment in C-ERM LMH was identified (p=0.001). The statistical analysis showed a significant association between the interruption of th outer retinal layers and A-ERM LMH (p<0.001) and between BCVA and integrity of external limiting membrane (p<0.001). Residual foveal thickness of A-ERM LMH showed a significant decrease at 24 months compared to timepoint 0 (p=0.027). Progressive increase of maximal diameter of intraretinal splitting of LMH in both ERM groups at 12 months and only in A-ERM LMH at 24 months (p=0.007) was demonstrated.
Conclusions :
A-ERM LMH is associated with a more severe clinical entity compared to C-ERM LMH. LMH is not a stable condition.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.