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Elena Zampedri, Rino Frisina, federica romanelli; Lamellar macular hole associated with epiretinal membrane. Clinical and morphological aspects.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4076.
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© ARVO (1962-2015); The Authors (2016-present)
To analyze the clinical and morphological characteristics of lamellar macular hole (LMH) associated with two distinctive epiretinal membranes (conventional C-ERM and atypical A-ERM).
Observational retrospective study of 189 eyes of 175 patients with LMH. Every cases of LMH presented an epiretinal membrane. The parameters analyzed were: demographic (age, gender, lens status), functional (best corrected visual acuity- BCVA) and tomographic (LMH type, presence of PVD, ERM type, integrity of ellipsoidal line and external limiting membrane, residual foveal thickness and maximal diamete of intraretinal splitting).
The mean BCVA was better in C-ERM LMH (p<0.001). A significant prevalence of female gender, phakic condition and posterior vitreous detachment in C-ERM LMH was identified (p=0.001). The statistical analysis showed a significant association between the interruption of th outer retinal layers and A-ERM LMH (p<0.001) and between BCVA and integrity of external limiting membrane (p<0.001). Residual foveal thickness of A-ERM LMH showed a significant decrease at 24 months compared to timepoint 0 (p=0.027). Progressive increase of maximal diameter of intraretinal splitting of LMH in both ERM groups at 12 months and only in A-ERM LMH at 24 months (p=0.007) was demonstrated.
A-ERM LMH is associated with a more severe clinical entity compared to C-ERM LMH. LMH is not a stable condition.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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