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Peter Maloca; Speckle-noise free choroidal angiography and vessel surface area measurement with Spectral OCT. Invest. Ophthalmol. Vis. Sci. 2016;57(12):455.
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© ARVO (1962-2015); The Authors (2016-present)
Approximately 95% of the ocular blood flow is directed to the uveal system, of which approximately 70% is circulating into the choroidal vessels. We visualize these vessels and measure their surface with speckle-noise freed 3D optical coherence tomography.
3DOCT volumes were obtained from 20 healthy eyes (10 females) with Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). The scan pattern was raster lines 4.5x3.0x1.9 mm, 261 B-Scans, with EDI-mode on, averaged for 20 scans using the automatic averaging and tracking tool. The OCT volumes were freed from speckle-noise with a prototype denoising analysis software. Choroidal vessels were segmented and their total surface area was calculated.
20 eyes of healthy females were investigated. The mean central choroidal vessel surface area was 0.18444301 mm2 (range 0.154483253 mm2 - 0.215696694 mm2; SD 0.01882505). Three dimensional models of the choroidal vessels were reconstructed.
Speckle-noise free chororoidal angiography and surface measurement may be a potential complementary 3D visualization technology for choroidal vessels.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
Speckle-noise free 3DOCT angiography of choroidal vessels.
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