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Avinash Gurbaxani, Darakhshanda Khurram; Ultra Wide Field Fundus Autofluroscence (UWF-FAF) for the detection and monitoring of inherited retinal disease in children. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1682.
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© ARVO (1962-2015); The Authors (2016-present)
Clinical features of inherited retinal disease are often difficult to detect in young children. This study aims to demonstrate the ease and utility of UWF-FAF in detecting and monitoring children with suspected inherited retinal disease particularly in the absence of electrophysiology.
Children with suspected inherited retinal disease were examined clinically and then underwent UWF-FAF imaging using the Optos tx-200 imaging system. Patients were aged between age 1 - 8 years. In total we examined 14 patients for the purpose of the study. Electrophysiology was not possible as it in not available in the country.
Image acquisition was relatively easy with the Optos imaging system even in the very small children. Good quality UWF_FAF images were obtained in 12 of the 14 patients. Known features of photoreceptor dystrophies were seen in all patients. Hyper auto fluorescent ring was seen in 10 patients.
UWF-FAF is a clinically useful tool in the detection and monitoring of inherited retinal disease in children. It is easy to use, quick and repeatable and provides important information in mamging these patients.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
Left eye UWF-FAF of a 3 year old boy with rod cone dystrophy secondary to NRL mutation
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