September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
IOL calcification after (triple-)DMEK
Author Affiliations & Notes
  • Silvia Schrittenlocher
    Eye Centre Cologne, University Hospital Cologne, Cologne, Germany
  • Marius Penier
    Eye Centre Cologne, University Hospital Cologne, Cologne, Germany
  • Björn Bachmann
    Eye Centre Cologne, University Hospital Cologne, Cologne, Germany
  • Claus Cursiefen
    Eye Centre Cologne, University Hospital Cologne, Cologne, Germany
  • Footnotes
    Commercial Relationships   Silvia Schrittenlocher, None; Marius Penier, None; Björn Bachmann, None; Claus Cursiefen, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1197. doi:
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      Silvia Schrittenlocher, Marius Penier, Björn Bachmann, Claus Cursiefen; IOL calcification after (triple-)DMEK. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1197.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : To identify factors promoting lens calcification after Descemet membrane endothelial keratoplasty (DMEK).

Methods : We retrospectively reviewed the charts of 311 patients who underwent DMEK either alone following previous cataract-surgery or in combination with cataract surgery (triple-DMEK) between September 2013 and June 2015 in our clinic for the occurrence of lens calcification. The charts were evaluated regarding type of gas tamponade, re-bubbling rate and intraocular lens (IOL) material.

Results : IOL calcifications occurred in 10 out of 311 patients (3.2%) after DMEK. 4 patients were already pseudophacic before DMEK surgery. In 6 out of 10 patients a triple-DMEK was performed. For catarcat surgery were used hydrophilic acrylic IOLs in 9 patients and hydrophobic IOL in one patient. Six patients underwent one, two patients two and one patient three additional rebubblings after DMEK. One patient did not require any additional intracameral gas injection. In one patient vision impairment necessitated an IOL exchange due to lens calcification. During DMEK surgery air was used for tamponade in 8 out of 10 patients. Two patients received sulfur hexafluoride (SF6) 20% during DMEK-operation. One of these 2 patients who received SF6 20% did not required any other rebubblings but still developed calcifications. Morphologically calcifications showed either cluster of small granular deposits or a more geographic configuration positioned in the optical center of the IOL.

Conclusions : IOL calcifications after DMEK is a newly recognized complication. It is associated with the type of IOL material (hydrophilic acrylate). Moreover, IOL calcifications can occur even if SF6 gas is used instead of room air for anterior chamber tamponade.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.




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