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Murilo Wendeborn Rodrigues, Jose A Cardillo, Emil Say, Felipe Borges, Rubens C Siqueira, Rodrigo Jorge; Reduced photoreceptor density over Choroid Nevus. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5099.
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© ARVO (1962-2015); The Authors (2016-present)
To assess macular photoreceptor abnormalities in eyes with posterior fundus choroid nevus lesion.
Cone density and spatial mosaic organization were assessed using adaptive optics scanning laser ophthalmoscopy (AO-SLO) images in three patients. Furthermore, color fundus, fluorescein angiography, microperimetry and Optic Coerence Tomography were performed.
Cone mosaic patterns were disorganized and dark regions missing wave-guiding cones were apparent. Correlation between reduced mean retinal sensitivity obtained using microperimetry and photoreceptor decreased density obtained using AO-SLO was noted.
AO images provide high-resolution en face images of the structural changes in Photoreceptor (PR) mosaic at the sites overlying the lesion. Attenuation of cone PRs appears to be an important early component of structural damage in nevus and maybe correlates or predicts functional loss
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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