September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Update on Mechanisms of Human Ocular Toxoplasmosis
Author Affiliations & Notes
  • Justine R Smith
    Flinders University, Adelaide, South Australia, Australia
    Australian Research Council, Canberra, South Australia, Australia
  • Footnotes
    Commercial Relationships   Justine Smith, None
  • Footnotes
    Support  NIH R21 EY019550, NHMRC 1066235, ARC FT130101648
Investigative Ophthalmology & Visual Science September 2016, Vol.57, No Pagination Specified. doi:
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      Justine R Smith; Update on Mechanisms of Human Ocular Toxoplasmosis. Invest. Ophthalmol. Vis. Sci. 2016;57(12):No Pagination Specified.

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      © ARVO (1962-2015); The Authors (2016-present)

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Presentation Description : Toxoplasma gondii is a ubiquitous Apicomplexan parasite that infects approximately 2 billion persons worldwide. Human infection with T. gondii tachyzoites manifests most often as an inflammation of the retina, which is frequently recurrent. This talk will review basic mechanisms of human ocular toxoplasmosis, as determined by studies using ocular cells and tissues that are isolated from human cadaver eyes. These mechanisms explain the extreme success of T. gondii as a human parasite, and indicate the challenges to be faced in developing more effective treatments for toxoplasmic retinochoroiditis.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.


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