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Justine R Smith; Update on Mechanisms of Human Ocular Toxoplasmosis. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© ARVO (1962-2015); The Authors (2016-present)
Presentation Description :
Toxoplasma gondii is a ubiquitous Apicomplexan parasite that infects approximately 2 billion persons worldwide. Human infection with T. gondii tachyzoites manifests most often as an inflammation of the retina, which is frequently recurrent. This talk will review basic mechanisms of human ocular toxoplasmosis, as determined by studies using ocular cells and tissues that are isolated from human cadaver eyes. These mechanisms explain the extreme success of T. gondii as a human parasite, and indicate the challenges to be faced in developing more effective treatments for toxoplasmic retinochoroiditis.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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