Abstract
Purpose :
To evaluate the changes in choroidal thickness and lamina cribrosa position after non penetrating deep sclerectomy (NPDS) and trabeculectomy.
Methods :
Twenty three eyes with glaucoma that required filtering surgery were included (12 NDPS and 11 trabeculectomies). OCT-enhanced depth imaging (OCT-EDI) was used to measure choroidal thickness, prelaminar tissue thickness and lamina cribrosa position before, and seven days and one month after surgery.
Results :
One week after surgery, the subfoveolar choroidal thickness (SFCT) significantly increased (416.65 ± 144.34 µm vs. 333.74 ± 144.9 µm; p = 0.04) and the prelaminar tissue was significantly thicker (279.09 ± 175 µm vs. 185.78 ± 135,74 µm ; p= 0,02) as compared to the preoperative state. These changes were not statistically significant at one month. There were no difference concerning these parameters between the NPDS and trabeculectomy groups. During the first week, changes in SFCT were correlated with intraocular pressure reduction (r = -0.39; p = 0.047).
Conclusions :
OCT-EDI allowed the visualization of structural changes at the level of the optic nerve and retinal vascularization during acute IOP changes. These structural changes may explain, at least in part, some severe complications of filtering surgery. No difference was observed between NPDS and trabeculectomy concerning these structural modifications.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.