September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes
Author Affiliations & Notes
  • BADR ALAHMADI
    vitreoretina, King Khalid Eye Specialist Hospital, Saudi Arabia, Madinah, Saudi Arabia
  • Sulaiman Alsulaiman
    vitreoretina, King Khalid Eye Specialist Hospital, Saudi Arabia, Madinah, Saudi Arabia
  • J. Fernando Arevalo
    Johns Hopkins University School of Medicine, The Wilmer Eye Institute, Baltimore, Maryland, United States
  • Footnotes
    Commercial Relationships   BADR ALAHMADI, None; Sulaiman Alsulaiman, None; J. Fernando Arevalo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 1054. doi:
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      BADR ALAHMADI, Sulaiman Alsulaiman, J. Fernando Arevalo; Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1054.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the functional and anatomic outcomes of retinal detachment (RD) surgery in patients with Down syndrome.

Methods : A retrospective chart review was performed of patients with Down syndrome who had undergone surgery for retinal detachment at King Khalid Eye Specialist Hospital between 1995 and 2014.

Results : A total of 245 patients with Down syndrome were evaluated during the study period. Eighteen eyes of 15 patients (6.1%) were identified. Three out of 15 patients (20%) presented with bilateral retinal detachment. All eyes presented with macula off retinal detachment. The retina was successfully reattached in 16/18 (88.8%) eyes after a mean follow up of 48 months. The final postoperative visual acuity ranged from light perception to 20/125 (median: hand motion) (11/18 eyes).

Conclusions : The retinal reattachment rate in patients with Down syndrome is comparable to other population groups. Patients with Down syndrome should undergo regular ophthalmic examinations for early diagnosis. Despite late diagnosis and the presence of proliferative vitreo-retinopathy (PVR) in some patients, favorable anatomical outcomes can be achieved.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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