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Jonathan G Crowston; Retinal ganglion cell structure and electrophysiology during injury and recovery. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© ARVO (1962-2015); The Authors (2016-present)
Presentation Description :
This presentation will detail function and structural changes in retinal ganglion cells in response to a sub-ischemic acute IOP injury that leads to low levels of RGC loss. We report RGC functional responses using full field ERG and single-cell patch clamping. We will also report on RGC structural changes up to 28 days following injury. These data show that RGCs can recover function after a prolonged period of functional loss and that structure and function correlate poorly during the recovery period.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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