Abstract
Purpose :
The purpose of this study was to characterize the visual performance of two daily disposable center-near design multifocal contact lenses in a population of established presbyopes, in terms of stereoacuity and areas-of-focus.
Methods :
70 established presbyopes (near add ≥+1.50) were enrolled in this observer-masked, randomized, crossover-investigation comparing nelfilcon A multifocal (DACP MF) with omafilcon A DD multifocal (P1D MF). After 5 (± 1) days of wear, visual performance measurements included stereoacuity with the Howard–Dolman system at distances of 40 and 60cm, contrast sensitivity measured using the VCTS test and binocular visual acuity measured with the ETDRS high-contrast logMAR chart under photopic conditions (85 cd/m2) to generate defocus curves. Areas of focus for the distance, intermediate, and near regions were calculated from the defocus curves.
Results :
In this population of established presbyopes, after 5(+/- 1) days of wear, DACP MF was shown to provide a significantly better stereoacuity at near (DACP MF: 30.7(12.96) P1D MF: 40.6(5.75) sec arc; LSM Difference (DACP MF - P1 DMF) = -9.81 (95% one-sided CI = -6.89)) and intermediate (DACP MF: 56.3(13.6) P1D MF: 70.1(14.5) sec arc; p<0.0001). Further, using defocus curves, no difference were recorded in the distance region, but larger areas-of-focus in the intermediate (LSM Difference (DACP MF - P1D MF) = 0.04 (95% one-sided CI = 0.02)) and near regions (LSM Difference (DACP MF - P1D MF) = 0.03 (95% one-sided CI = 0.02)) were demonstrated for DACP MF compared to P1D MF correction.
Conclusions :
Whereas both DACP MF and P1D MF performed generally well in this study, near and intermediate stereopsis measurements as well as the area-of-focus metrics assessed were able to differentiate between these two multifocal center-near lenses with different add designs. In the intermediate and near regions, DACP MF contact lenses demonstrated greater depth perception/less compromise in binocular function (better stereopsis) and greater area-of- focus.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.